Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- For the REACH registration of dilithium tetraborate, a theoretical statement was prepared stating that in accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate. This statement is also applicable for Reaction products of boric acid and calcium dihydroxide and lithium hydroxide as the target UVCB substance has a higher precursor molar ratio for lithium hydroxide than for calcium hydroxide, and therefore the precautionary principle should be applied and read across from dilithium tetraborate where relevant to consider the worst case. Read across to the theoretical statement prepared for dilithium tetraborate is proposed to cover the adosprtion/desorption endpoint for the REACH registration of Reaction products of boric acid and calcium dihydroxide and lithium hydroxide.
- Reason / purpose for cross-reference:
- read-across source
- Remarks on result:
- not determinable because of methodological limitations
- Remarks on result:
- not determinable because of methodological limitations
- Validity criteria fulfilled:
- yes
- Conclusions:
- The study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as Reaction products of boric acid and calcium dihydroxide and lithium hydroxide.
- Executive summary:
For the REACH registration of dilithium tetraborate, a theoretical statement was prepared stating that in accordance with the REACH Regulation, the study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate. This statement is also applicable for Reaction products of boric acid and calcium dihydroxide and lithium hydroxide. Read across to the theoretical statement prepared for dilithium tetraborate is proposed to cover the adosprtion/desorption endpoint for the REACH registration of Reaction products of boric acid and calcium dihydroxide and lithium hydroxide.
Reference
Description of key information
The study on the adsorption coefficient (Koc) on soil and on sewage sludge cannot be performed using High Performance Liquid Chromatography (HPLC) method as described in OECD guideline 121 for an inorganic substance or mineral salt test item such as dilithium tetraborate.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
