6-diazo-5,6-dihydro-5-oxonaphthalene-2-sulphonyl chloride

Biodegradation in water: screening tests

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

biodegradation in water: ready biodegradability

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

March - September 2018

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

study well documented, meets generally accepted scientific principles, acceptable for assessment

Justification for type of information:

The supporting information provided has been gathered in preparation of the ecotoxicity testing battery. Analytical investigations show, that a rapid initial degradation is observed (half life < 24 h) and the degradation products have been identified. These degradation products, however must be considered not ready biodegradable. This analytical information is supporting the QSAR result observed and reported.

Reason / purpose for cross-reference:

reference to other study

Oxygen conditions:

aerobic

Duration of test (contact time):

24 h

Initial conc.:

4.4 g/L

Based on:

test mat.

Parameter followed for biodegradation estimation:

test mat. analysis

Validity criteria fulfilled:

not applicable

Interpretation of results:

not readily biodegradable

Conclusions:

Not readily biodegradable after initial decomposition

Reference 2

Endpoint:

biodegradation in water: screening test, other

Remarks:

calculation

Type of information:

calculation (if not (Q)SAR)

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

results derived from a valid (Q)SAR model and falling into its applicability domain, with limited documentation / justification

Guideline:

other: QSAR

Specific details on test material used for the study:

chemical structure was used as input

Key result

Parameter:

half-life in days (QSAR/QSPR)

Value:

> 28

Sampling time:

28 d

Remarks on result:

not readily biodegradable based on QSAR/QSPR prediction

Details on results:

CAS Number:
SMILES : CLS(=O)(=O)c1ccc2C(=O)C(=N#N)C=Cc2c1
CHEM :
MOL FOR: C10 H5 CL1 N2 O3 S1
MOL WT : 268.68
--------------------------------- Biowin Summary ----------------------------------------------

Probability of Rapid Biodegradation (BIOWIN v4.10):
Biowin1 (Linear Model) : 0.6265
Biowin2 (Non-Linear Model) : 0.2211
Expert Survey Biodegradation Results:
Biowin3 (Ultimate Survey Model): 2.5830 (weeks-months)
Biowin4 (Primary Survey Model) : 3.4379 (days-weeks )
MITI Biodegradation Probability:
Biowin5 (MITI Linear Model) : 0.0583
Biowin6 (MITI Non-Linear Model): 0.0236
Anaerobic Biodegradation Probability:
Biowin7 (Anaerobic Linear Model): -0.4268
Ready Biodegradability Prediction: NO

Interpretation of results:

not readily biodegradable

Description of key information

The test item is not readily biodegradable based on QSAR prediction. These findings are supported by analytical data showing a fast initial decomposition to products that are not readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:

under test conditions no biodegradation observed

Type of water:

freshwater