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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

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Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 471 (Bacterial Reverse Mutation Assay)
Deviations:
no
GLP compliance:
yes
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
Amines, N-coco alkyltrimethylenedi-, acetates
EC Number:
263-196-9
EC Name:
Amines, N-coco alkyltrimethylenedi-, acetates
Cas Number:
61791-64-8
Molecular formula:
H17-37C8-18NH(CH2)3NH2. (H3CCOOH)2
IUPAC Name:
Amines, N-coco alkyltrimethylenedi-, acetates
Test material form:
solid

Results and discussion

Test resultsopen allclose all
Key result
Species / strain:
E. coli WP2 uvr A
Key result
Species / strain:
S. typhimurium TA 100
Key result
Species / strain:
S. typhimurium TA 98
Key result
Species / strain:
S. typhimurium TA 1537
Key result
Species / strain:
S. typhimurium TA 1535
Remarks on result:
other: investigation is ongoing (test item determined to be cytotoxic to five bacterial strains but non-mutagenic)

Applicant's summary and conclusion

Conclusions:
The bacterial reverse mutation assay is ongoing. Interim results show that the substance is cytotoxic to five bacterial strains but non-mutagenic.
Executive summary:

The bacterial reverse mutation assay is ongoing. Interim results show that the substance is cytotoxic to five bacterial strains but non-mutagenic.