Registration Dossier
Registration Dossier
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EC number: 238-961-5 | CAS number: 14887-42-4
Vapour pressure
Administrative data
Link to relevant study record(s)
- Endpoint:
- vapour pressure
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From: 02/02/2010 To: 03/02/2010
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.4 (Vapour Pressure)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 104 (Vapour Pressure Curve)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 30/03/2009
- Type of method:
- other: isothermal thermogravimetric Effusion method.
- Temp.:
- 20 °C
- Vapour pressure:
- < 0.001 Pa
- Transition / decomposition:
- yes
- Transition temp.:
- >= 110.01 °C
- Conclusions:
- The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Potassium pentahydrogen bis(phosphate). The vapour pressure of the test substance at 20°C was <1.47¯³ Pa.
This study is conducted according to an appropriate guideline and under the conditions of GLP and therefore the study is considered to be acceptable and to adequately satisfy both the guideline requirement and the regulatory requirement as a key study for this endpoint.
Reference
The weight loss of the test substance at 110, 120, 130 and 140 °C was lower than the weight loss of hexachlorobenzene at the same temperatures. From this it was concluded that the vapour pressure of the test substance is < 1.47x10³.
Table 1 - Evaporation in µ/minute
Temperature |
Weight loss µg/min |
|
Test substance |
Reference substance (hexachlorobenzene) |
|
110 |
-0.3164 |
-16.44 |
120 |
-0.8715 |
-36.92 |
130 |
-1.517 |
-73.10 |
140 |
-9.670 |
-138.1 |
Description of key information
One key study exists. This study (Brekelmans MJC, 2010) was conclusive, done to a valid guideline (EU Method A.4) and the study was conducted under GLP conditions. It is therefore scientifically justified for use as a key study under Regulation (EC) No. 1907/2006.
Key value for chemical safety assessment
- Vapour pressure:
- 0.001 Pa
- at the temperature of:
- 20 °C
Additional information
The isothermal thermogravimetric effusion method was chosen for the determination of the vapour pressure of Potassium pentahydrogen bis(phosphate). The vapour pressure of the test substance at 20°C was <1.47¯³ Pa.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
