Registration Dossier
Registration Dossier
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EC number: 229-761-9 | CAS number: 6711-48-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2012-02-07- 2012-02-13
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): bis-DMAPA
- Substance type: Amber liquid
- Physical state: Liquid
- Composition of test material, percentage of components: 0.03% water, 16.02 meq/g total amine
- Lot/batch No.: PFW110019
- Storage condition of test material: Sample stored in cool, well-ventilated storage area prior to testing - Key result
- Water solubility:
- 425.07 g/L
- Conc. based on:
- test mat.
- Temp.:
- 20 °C
- pH:
- 12.68 - 12.88
- Remarks on result:
- other: The reported result is the average of 3 flasks.
- Water solubility:
- 873 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Temp.:
- 20 °C
- pH:
- 12.68 - 12.88
- Remarks on result:
- other: The reported result is the average of 3 flasks.
- Details on results:
- As the solubility of the test item was found to be greater than 100 g/L in solution a correction factor was applied to determine the solubility of the material in 1 L of water. Both results have been reported: 873 g test material dissolves in 1L water; expressed as solubility in the final solution, this corresponds to 425.07 g/L.
- Conclusions:
- Interpretation of results: very soluble (> 10000 mg/L)
The substance is concluded to be very soluble in water at ambient temperature: max 873 g test material dissolves in 1L water; expressed as solubility in the final solution, this corresponds to 425.07 g/L.
Reference
During the aqueous solubility estimation stage of the test, 833.57 mg of the sample completely dissolved in 5.5 mL of water.
Description of key information
In a GLP-compliant study according to the preliminary test as specified in test method EC A.6, the test substance was determined to be very soluble in water under ambient conditions (Younis S, 2012).
Key value for chemical safety assessment
- Water solubility:
- 425 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility is 425 g/L solution; this corresponds to 873 g test material that will dissolve in 1L water.
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