Registration Dossier
Registration Dossier
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EC number: 211-684-7 | CAS number: 685-88-1
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- other company data
- Title:
- Unnamed
- Year:
- 2 005
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Screening test
- GLP compliance:
- no
Test material
- Reference substance name:
- Diethyl fluoromalonate
- EC Number:
- 211-684-7
- EC Name:
- Diethyl fluoromalonate
- Cas Number:
- 685-88-1
- Molecular formula:
- C7H11FO4
- IUPAC Name:
- 1,3-diethyl 2-fluoropropanedioate
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- shaved
- Vehicle:
- physiological saline
- Controls:
- no
- Duration of treatment / exposure:
- 4 hours
- Number of animals:
- 1
Results and discussion
Any other information on results incl. tables
The animal was sacrificed for ethical reason 3 hours after the treatment and no irritation score was performed.
Applicant's summary and conclusion
- Interpretation of results:
- Category 1C (corrosive)
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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