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Diss Factsheets
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EC number: 225-464-3 | CAS number: 4861-19-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Urea phosphate will directly dissociate into urea and phosphoric acid in aqueous environment. Considering all data, this shows that urea phosphate is of very low toxicity to aquatic organisms with effect values all above 100 mg/L when the duration of exposure was as specified within the current guidelines.
Toxicity to fish
Urea: The 96 hour LC50of urea to B. barnawas > 9100 mg/L. The NOEL was 4961 ppm.
Phosphoric acid: The median lethal pH (96 hr) was 3 -3.35 for Lepomis macrochirus. Mortality is caused by low pH values, when adjusted to environmentally relevant pH values, phosphoric acid does not cause acute adverse effects.
No long-term toxicity data are available: Urea and phosphoric acid do have a very high water solubility and its chemical properties do not indicate bioaccumulation. In addition, urea is of inherently low toxicity to fish species: it is a normal product of protein catabolism and therefore fish have evolved effective excretion mechanisms. Additionally, exposure will be limited by the action of microorganisms and incorporation of urea into the nitrogen cycle.
Toxicity to aquatic invertebrates
The 24 hour EC50 for urea in Daphnia was reported to be >10000 mg/L; urea is not acutely toxic to daphnids.
The 48h-EC50 for phosphoric acid in Daphnia was >100 mg/L.
No long-term toxicity data are available: Urea and phosphoric acid do have a very high water solubility and its chemical properties do not indicate bioaccumulation. In addition, urea is of inherently low toxicity to invertebrate species: it is a normal product of protein catabolism and therefore fish have evolved effective excretion mechanisms. Additionally, exposure will be limited by the action of microorganisms and incorporation of urea into the nitrogen cycle.
Toxicity to algae
The 192 hour toxicity threshold of blue-green algae urea was 47 mg/L. To some extent urea exhibits toxic action to Microcystis aeruginosa. The 7 day toxicity threshold of urea to Scenedesmus quadricauda was >10000 mg/L.
The 72 hour EC50 for phosphoric acid with Desmodesmus Subspicatus (the pH was adjusted to neutral (pH 7.5)) was >100mg/L and NOEC=100 mg/L.
Toxicity to Micro-organisms
The 3-hour EC50 value for urea phoshate to activated sludge was >100 mg/L with a NOEC of 100 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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