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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: OECD guideline used

Data source

Reference
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes

Test material

Constituent 1
Reference substance name:
4-aminotoluene-3-sulphonic acid
EC Number:
201-831-3
EC Name:
4-aminotoluene-3-sulphonic acid
Cas Number:
88-44-8
IUPAC Name:
2-amino-5-methylbenzenesulfonic acid
Details on test material:
Wako Pure Chemical Industries, Ltd.: purity >95%

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Daphnia magna

Study design

Test type:
static
Limit test:
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
10 mg/L
Duration:
48 h
Dose descriptor:
EC0
Effect conc.:
> 10 mg/L
Duration:
48 h
Dose descriptor:
EC50
Effect conc.:
> 10 mg/L

Any other information on results incl. tables

CONCENTRATIONS
nominal concent-       measured concentration (mg/L)
ration (mg/L)               0hr              48hr
------------------------------------------------------------
control                     <0.1             <0.1
solvent control           <0.1             <0.1
  10                       9.8               10
As the result, measured concentration was equivalent (99%)
to nominal ones.
EFFECTS
No immobilized or abnormal movement one was observed in any
those dose levels.
MONITORING DATA
water temperature: 19.6°C
dissolved oxygen: 8.3-8.7mg/L
               (Saturated concentration at 20°C is 8.8mg/L.)
pH: 8.0-8.2
REMARK
This study was limit test at 10mg/L only, due to author's
misunderstanding to the solubility in water. Therefore it was not a real limit test.

Applicant's summary and conclusion

Conclusions:
48hr LC50 (and LC0) of Daphnia magna is > 10mg/L.