Registration Dossier
Registration Dossier
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EC number: 629-671-3 | CAS number: 1522-41-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 420 (Acute Oral Toxicity - Fixed Dose Method)
- GLP compliance:
- yes
- Test type:
- fixed dose procedure
Test material
- Reference substance name:
- ethyl 2-fluoro-3-oxobutanoate
- EC Number:
- 629-671-3
- Cas Number:
- 1522-41-4
- Molecular formula:
- C6H9FO3
- IUPAC Name:
- ethyl 2-fluoro-3-oxobutanoate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
Administration / exposure
- Route of administration:
- oral: gavage
- Vehicle:
- arachis oil
- Doses:
- 50 mg/kg and 300 mg/kg
- No. of animals per sex per dose:
- 5 subjects at 50 mg/kg
1 subject at 300 mg/kg - Control animals:
- no
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- discriminating dose
- Effect level:
- > 50 - < 300 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Remarks:
- Migrated information
- Conclusions:
- The acute oral median lethal dose (LD50) of the test item in the female Wistar strain rat was estimated to be in the range of 50 - 300 mg/kg body weight (Globaly Harmonised Classification System - Category 3).
- Executive summary:
The acute oral median lethal dose (LD50) of the test item in the female Wistar strain rat was estimated to be in the range of 50 - 300 mg/kg body weight (Globaly Harmonised Classification System - Category 3).
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