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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

A 0.5% concentration of p-tert-butylbenzaldehye in propylene glycol was not irritating to rabbit eyes.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
no study available

Eye irritation

Link to relevant study records
Reference
Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Proprietary study conducted in 1979, only a brief report containing the endpoint is available
Qualifier:
no guideline available
Principles of method if other than guideline:
Draize method
GLP compliance:
no
Species:
rabbit
Strain:
not specified
Details on test animals or tissues and environmental conditions:
No further details available.
Vehicle:
other: propylene glycol
Controls:
not specified
Amount / concentration applied:
0.5% prepared in propylene glycol
Duration of treatment / exposure:
No information available.
Observation period (in vivo):
No information available.
Number of animals or in vitro replicates:
No information available.
Details on study design:
No information available.
Irritation parameter:
other: irritation
Remarks on result:
other: no effects observed
Irritant / corrosive response data:
No eye irritation was observed following exposure to 0.5% test material in propylene glycol.
Other effects:
None reported.

No further information available.

Conclusions:
A 0.5% concentration of p-tert-butylbenzaldehye in propylene glycol was not irritating to rabbit eyes.
Executive summary:

A 0.5% concentration of p-tert-butylbenzaldehye in propylene glycol was not irritating to rabbit eyes.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not irritating)

Additional information

A 0.5% concentration of p-tert-butylbenzaldehye in propylene glycol was not irritating to rabbit eyes.


Justification for selection of eye irritation endpoint:
Only one study is available

Justification for classification or non-classification

A 0.5% concentration of p-tert-butylbenzaldehye in propylene glycol was not irritating to rabbit eyes, therefore no classification is required for this concentration level.