Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

In an acute oral toxicity study in rats according to a method similar or equivalent to EU method B.1 and OECD guideline 401 the LD50 was determined to be 1410 mg/kg bw for males and 1620 mg/kg bw for females. In an acute inhalation study in rats according to EU method B.2 and OECD guideline 403 the 4 hour LC50 was determined to be > 21.3 mg/L. In an acute dermal toxicity study in rats according to EU method B.3 and OECD guideline 402 to LD50 was determined to be > 2000 mg/kg bw.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
Value:
1 410 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
Value:
21 300 mg/m³ air

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
Value:
2 000 mg/kg bw

Additional information

Justification for classification or non-classification

Based on the data available the substance is classified and labeled Xn; R22 Harmful; Harmful if swallowedaccording to Directive 67/548/EEC (DSD) and Acute Tox. 4 H302: Harmful if swallowed according to Regulation 1272/2008/EC (CLP).