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EC number: 263-061-4 | CAS number: 61789-45-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No short-term toxicity effects up to the limit of water solubility expected.
Key value for chemical safety assessment
Additional information
No study is available on short-term toxicity of fatty acids, dehydrated castor-oil (CAS 61789 -45 -5) to fish. Therefore ecotoxicological effects are predicted from adequate and reliable data for source substance(s) within the group by read-across to the target substances in the group applying the group concept in accordance with Annex XI, Item 1.5, of Regulation (EC) No 1907/2006.
The main constituents of the mixture are C18'' and C18'' conjugated. As for both constituents no acute fish test is available read-across is performed to the unsaturated C18', oleic acid (CAS 112 -80 -1) which is also a member of the fatty acids category. Furthermore, a supporting read across is performed to fatty acids, tall oil (CAS 61790 -12 -3), since the main components of this fatty acid mixture are also unsaturated C18 components (50 -60% C18', 35 -40% C18'').
In the study provided from the Ministry of the Environment, Government of Japan (2002), oleic acid C18' was tested as limit test according to OECD 203 under GLP-conditions. In the semi-static test the LC 50 (96 h) was reported to be > 2.5 mg/L based on mean measured concentrations (corresponding to > 3.6 mg/L based on nominal concentrations). Thus no effect within the range of water solubility could be detected.
The suppporting study on toxicity to fish with fatty acids, tall oil was condcuted according to OECD 203 under GLP conditions (Pine Chemical Association, 2004). Fathead minnow (Pimephales promelas) was exposed to water accomodated fractions (WAF) of 1, 10, 100 and 1000 mg/L (nominal). Since no mortality was observed up to the highest loading rate a LL50 (96h) of > 1000 mg/L was stated. Thus no effect up to the limit of water solubility could be detected.
Taking into account the stated results no short-term effects on fish of fatty acids, dehydrated castor-oil (CAS 61789 -45 -5) are expected up to the limit of water solubility.
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