Registration Dossier
Registration Dossier
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EC number: 687-538-5 | CAS number: 18423-20-6
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 006
- Report date:
- 2006
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- EU Method C.1 (Acute Toxicity for Fish)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane nitrate
- EC Number:
- 687-538-5
- Cas Number:
- 18423-20-6
- Molecular formula:
- C6H13N5O3
- IUPAC Name:
- 3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane nitrate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: Pez Cebra o Mero Rayado
- Source: Colonia estabilizada en laboratorio
- Feeding during test
- Food type: ad libitum
- Frequency: daily
ACCLIMATION
- Acclimation conditions (same as test or not):22 ºC (+/- 1ºC)
- Type and amount of food: ad libitum
- Feeding frequency: daily
Study design
- Test type:
- not specified
- Water media type:
- freshwater
- Total exposure duration:
- 96 h
Test conditions
- Hardness:
- 80+/- 3 mg CaCO3/L
- Test temperature:
- 22ºC (+/- 1ºC)
- pH:
- 7.9 +/- 0.3
- Dissolved oxygen:
- To saturation
- Reference substance (positive control):
- not specified
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 96 h
- Dose descriptor:
- LC50
- Effect conc.:
- > 200 mg/L
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- ca. 200 mg/L
- Duration:
- 96 h
- Dose descriptor:
- LOEC
- Effect conc.:
- > 200 mg/L
Any other information on results incl. tables
- Sublethal observations / clinical signs:
N/Ref 1555 CONCENTRACIÓN (mg/L) S/Ref Sol. Nitrato de Hexamina Control (-) 12.5 25 50 100 200 Mortalidad (Nº organismos afectados 24 h) 0/20 0/20 0/20 0/20 0/20 0/20 Mortalidad (Nº organismos afectados 48 h) 0/20 0/20 0/20 0/20 0/20 0/20 Mortalidad (Nº organismos afectados 72 h) 0/20 0/20 0/20 0/20 0/20 0/20 Mortalidad (Nº organismos afectados 96 h) 0/20 0/20 0/20 0/20 0/20 0/20
Applicant's summary and conclusion
- Conclusions:
- C(E)L50 (96 h) (Danio rerio) > 200 mg/L.
- Executive summary:
Según los resultados obtenidos en este ensayo, la toxicidad aguda C(E)L50 (96 h) sobre Pez Cebra (Danio rerio) producida por la muestra 1555 se ha valorado en > 200 mg/L.
De acuerdo con los criterios de clasificación establecidos en el anexo VI del RD 363/1999 sobre notificación de sustancias nuevas y Clasificación,Envasado y Etiquetado de Sustancias Peligrosas, las sustancias o preparados con una C(E)L50 (96) para peces (Danio rerio) superior a 100 mg/L no se clasifican en ninguna de las categorias de peligrosidad (muy tóxico, tóxico o nocivo) por los organismos acuáticos.
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