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EC number: 243-094-0 | CAS number: 19473-49-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- method according to Siwoloboff
Test material
- Reference substance name:
- 5-potassium hydrogen L-glutamate
- EC Number:
- 243-094-0
- EC Name:
- 5-potassium hydrogen L-glutamate
- Cas Number:
- 19473-49-5
- Molecular formula:
- C5H9NO4.K
- IUPAC Name:
- potassium 5-oxido-5-oxo-L-norvaline
- Test material form:
- solid
1
- Specific details on test material used for the study:
- Test item: L-GLUTAMIC ACID MONOPOTASSIUM SALT
MONOHYDRATE
CAS No.: 6382-01-0
Appearance: White powder
Batch number: SLCJ1327
Manufacturing date: 15.12.2020
Expiry date: 01.12.2022
Producer: Sigma-Aldrich Handels GmbH
Sample code: 46/21
Storage temperature range: 10-25 ̊C
Results and discussion
Boiling point
- Key result
- Atm. press.:
- ca. 101 325 Pa
- Decomposition:
- yes
- Decomp. temp.:
- ca. 205 °C
- Remarks on result:
- not determinable because of methodological limitations
Applicant's summary and conclusion
- Conclusions:
- Boiling point was not determined – test item decomposes and the decomposition process
starts at about 205 °C. - Executive summary:
Boiling point was not determined – test item decomposes and the decomposition process
starts at about 205 °C.Determination of the boiling point was performed in accordance with the Standard Operating
Procedure SPO/BS/26/b (edition 5). The boiling point determination using capillary tube in
metal block was performed according to EC method A.2 “Boiling temperature” (1.4.4.
Method according to Siwoloboff), which is in conformity with the OECD Guideline for
Testing of Chemicals no. 103 “Boiling point”.
The capillary tube in heated metal block method and BÜCHI Melting Point M-565 apparatus
was used. A sample of the test item was poured into a boiling point tube. The level of sample
was 5-10 mm. A boiling point capillary was inserted into the boiling point tube with its open
end. The capillary tube with a sample of test item and an inner capillary was placed in a
heated metal block.
The sample of test item was heated in a boiling point tube under atmospheric pressure. In the
preliminary test the temperature was increased at a rate of 10 °C/min to determine
approximate value of boiling point. The sample has not achieved the boiling point, it started
to decompose. During the final test the initial test temperature was 120 °C and the heating rate
was decreased to 5 °C/min to observe the changes of the sample more precisely.Preliminary test
The study was carried out in order to determine the boiling temperature range for LGLUTAMIC ACID MONOPOTASSIUM SALT MONOHYDRATE (in the range of 110.0 –
400.0 °C). The boiling point was not determined due to the decomposition process which was
observed during the study execution. Detailed observation of the sample was carried out
during the ‘final test’.
Final test
The sample was heated in the temperature range of 120-400 °C. At about 130 °C some gas
bubbles started to liberate – the hydration water was expelled from the sample. At about 154
°C the process stopped and the substance became solidified. Then, at about 205 °C, the
sample melted and gas bubbles were very slowly liberated from the capillary – the
decomposition process was initiated. At about 275 °C tint of the sample started to change to
straw. The decomposition process was observed until about 350 °C, when the sample was
dark brown and started to raise in the capillary.
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