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Physical & Chemical properties

Vapour pressure

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Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
6 June 2018 to 11 June 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23 March 2006
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
gas saturation method
Specific details on test material used for the study:
- Storage conditions: The test material was stored in a dark storage place at room temperature.
- Test material identification and stability under storage: The infrared (IR) spectrum of the test material measured at the test facility was confirmed to be identical to that provided by the sponsor. In addition, the IR spectrum of the test material after the completion of the experiment was the same as that before the start of the experiment, and it indicated that the test material was stable under storage conditions.
Key result
Test no.:
#1
Temp.:
25 °C
Vapour pressure:
< 0 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Vapour pressure:
< 0 Pa

As the results of the analysis of test solutions, the test material was not detected on the chromatogram. Therefore, the vapour pressure of the test material was calculated from the limit of determination and regarded as less than the calculated value. 

Conclusions:
Under the conditions of this study the vapour pressure of the test material was < 1.68 x 10^-5 Pa at 25 °C.
Executive summary:

The vapour pressure of the test material was investigated according to the standardised guideline OECD 104 and under GLP conditions, using a gas saturation method.

In the preliminary test, the test temperature was set at 80 °C with a flow rate of 40 mL/min. The result of the analysis of the test solution showed that the test material was not detected on the chromatogram. The main test was conduced at 25 °C with a flow rate of 40 mL/min using HPLC. As the results of the analysis of test solutions, the test material was not detected on the chromatogram. Therefore, the vapour pressure of the test material was calculated from the limit of determination and regarded as less than the calculated value.

Under the conditions of this study the vapour pressure of the test material was < 1.68 X 10^-5 Pa at 25 °C.

Description of key information

The vapour pressure of the test material was < 1.68 X 10^-5 Pa at 25 °C.

Key value for chemical safety assessment

Vapour pressure:
0 Pa
at the temperature of:
25 °C

Additional information

The vapour pressure of the test material was investigated according to the standardised guideline OECD 104 and under GLP conditions, using a gas saturation method. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

In the preliminary test, the test temperature was set at 80 °C with a flow rate of 40 mL/min. The result of the analysis of the test solution showed that the test material was not detected on the chromatogram. The main test was conduced at 25 °C with a flow rate of 40 mL/min using HPLC. As the results of the analysis of test solutions, the test material was not detected on the chromatogram. Therefore, the vapour pressure of the test material was calculated from the limit of determination and regarded as less than the calculated value.

Under the conditions of this study the vapour pressure of the test material was < 1.68 X 10^-5 Pa at 25 °C.