2-ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

11 Mar 2020 - 23 Apr 2020

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

March 04, 2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

March 1998

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Type of method:

differential scanning calorimetry

Specific details on test material used for the study:

Physical Description: Colourless to pale yellow liquid (determined by Charles River Den Bosch)
Purity/Composition: 96.27%
Storage Conditions: At room temperature
Purity/Composition correction factor: No correction factor required
Test item handling: No specific handling conditions required
Chemical name : 2-Ethylhexyl 2-([1,1'-biphenyl]-4-ylcarbonyl)benzoate
CAS number: 75005-95-7
EC Number: 278-051-5
Molecular formula: C28H30O3
Molecular weight: 414.22

Remarks on result:

other: No melting point was determined. A glass transition of the test item was observed at -32.5°C (240.6K).

Preliminary Test

The TGA curve of the test item is shown in Figure 1. Starting at 275°C, the weight of the sample decreased significantly. At 375°C, the sample weight had decreased by 25%.

After the experiment, a black molten residue remained in the sample container (original colour: colourless to pale yellow liquid). The change of the colour indicated reaction and/or decomposition of the test item.

Main Study

The DSC curve obtained with Experiment 1 is shown in Figure 2. During cooling a glass transition was observed between -20°C and -60°C (results are archived in the raw data).

During heating a glass transition was observed between -50°C and 0°C followed by an endothermic effect starting at 250°C. The inflection point temperature of the glass transition was -32.302°C. The endothermic effect was probably obtained due to reaction and/or decomposition of the test item.

After the experiment, a dark brown molten residue remained in the sample container (original colour: colourless to pale yellow liquid). Based on this visual observation, it was found that the test item had molten and the change of the colour demonstrated reaction and/or decomposition of the test item.

Experiment 2 was performed as a duplicate of the glass transition temperature of Experiment 1. Figure 3 shows the DSC curve obtained. Similar results as in Experiment 1 were obtained. The inflection point temperature of the glass transition effect was -32.795°C. After the experiment, the remained residue in the sample container was unchanged.

The melting temperature was determined as the mean melting temperature of Experiment 1 (-32.302°C) and Experiment 2 (32.795°C).

Conclusions:

No melting point was determined. A glass transition of the test item was observed at -32.5°C (240.6K).

Executive summary:

In this guideline (OECD 102) study, conducted with GLP certification, no melting point was determined. A glass transition of the test item was observed at -32.5°C (240.6K).

Description of key information

Study conducted to recognised testing guidelines with GLP certification.

Additional information

No melting point was determined. A glass transition of the test item was observed at -32.5°C (240.6K).