Registration Dossier
Registration Dossier
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EC number: 811-285-3 | CAS number: 1637294-12-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- April 21, 2015 to June 05, 2015
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Name (as stated in the report): GR-88-0778
Lot No: Batch 6
Aspect: Colourless liquid
Expiration date: March 29, 2017 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 3.7
- Temp.:
- 35 °C
- pH:
- 7
- Conclusions:
- In the conditions of the test, the chromatograms of GR-88-0778 show one peak at an average retention time of 7.628 minutes, corresponding to a partition coefficient (log value) of 3.7.Therefore:Partition coefficient n-octanol/water of GR-88-0778: log Pow = 3.7N.B.: The determination was performed at 35°C (temperature of the column), but the value obtained above can be considered to represent the value at an unspecified, probably ambient temperature since no mention is made in the guidelines of the temperature at which the tabulated reference substances log Pow values were determined. Partition coefficients of the test and reference substances are assumed to vary with temperature in the same way.
- Executive summary:
The Partition Coefficient n-octanol/water of GR-88-0778 was determined by the Reverse Phase High Performance Liquid Chromatographic Method according to the OECD Guidelines for Testing of Chemicals, Method No. 117.
The result is:
Partition coefficient n-octanol/water of GR-88-0778: log Pow= 3.7
Reference
Description of key information
The Partition Coefficient n-octanol/water of GR-88-0778 was determined by the Reverse Phase High Performance Liquid Chromatographic Method according to the OECD Guidelines for Testing of Chemicals, Method No. 117.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.7
- at the temperature of:
- 35 °C
Additional information
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