Benzenesulfonic acid, 4-C15-16-sec-alkyl derivs.-, compd. with 1-aminopropane-2-ol

Dissociation constant

Link to relevant study record(s)

Reference

Endpoint:

dissociation constant

Type of information:

experimental study

Adequacy of study:

key study

Study period:

March 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 112 (Dissociation Constants in Water)

GLP compliance:

no

Other quality assurance:

ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: MI16A047

Dissociating properties:

yes

No.:

#1

pKa:

2.6

Temp.:

20 °C

	Salt concentration of solution (g/l)	Molarity of solution (g/mol)	Molar conductivity (µS/cm/mole)	Degree of dissociation (α)	Dissociation constant
Solution 4	4.9660	0.0111	13784	0.32	0.0017
Solution 5	2.5380	0.0057	21228	0.49	0.0027
Solution 6	1.2690	0.0028	28464	0.66	0.0036
Solution 7	0.6345	0.0014	32786	0.76	0.0034
Solution 8	0.3173	0.0007	37143	0.86	0.0038
Solution 9	0.1586	0.0004	35750	0.83	0.0016
Solution 10	0.0793	0.0002	38500	0.89	0.0015
Solution 11	0.0397	0.0001	41000	0.95	0.0019

#

#

Average dissociaiton constant = 0.0025

Standard deviation of dissociation constant = 0.0010

pK_c = 2.60

Conclusions:

The dissociaiton constant is 2.60.

Executive summary:

In an OECD guideline study (OECD 112), the dissociation of Marlon AMI 80 has been investigated. The dissociation constant is found to be 2.40.

Description of key information

In a OECD guideline study (OECD 112) the dissociation constant has been measured. The pKc is 2.6.

Key value for chemical safety assessment

pKa at 20°C:

2.6