Registration Dossier
Registration Dossier
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EC number: 212-216-4 | CAS number: 770-05-8
Auto flammability
Administrative data
Link to relevant study record(s)
- Endpoint:
- relative self-ignition temperature (solids)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: UN N4 Self-heating temperature by the Modified Bowes-Cameron Cage test, solid (UN N.4)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Identification: Octopamine hydrochloride
Appearance: White to off white powder (determined by
Charles River Den Bosch)
Batch: D151-1710037
Purity/Composition: 99.8% w/w
Test item storage: At room temperature protected from light
Stable under storage conditions until: 26 October 2019 (retest date)
Additional information - Remarks on result:
- no self ignition observed under the test conditions
- Conclusions:
- Self-heating of Octopamine hydrochloride was determined in accordance with UN Test N.4
“Test Method for Self-heating Substances”.
From the negative result obtained at 140°C using a 10 cm sample cube, it was concluded that
Octopamine hydrochloride is not a self-heating substance.
Reference
The plots of the oven temperature and sample temperature versus time are shown in Figure 6.
An exothermic effect of the test item by self-heating was observed at an oven temperature of
139.7°C. During this effect the test item reached a temperature of 152.4°C. According to the
guideline, the test is positive when the sample temperature exceeds the oven temperature by
60°C during the 24 hour testing time. Based on this, the result is considered negative and it
demonstrated that the test item is “not a self-heating substance”. According to the UN
guideline, no further testing is required.
After the experiment, the test item had turned into a brown residue. It indicated that the test
item had decomposed and/or reacted during the experiment.
Description of key information
Self-heating of Octopamine hydrochloride was determined in accordance with UN Test N.4 “Test Method for Self-heating Substances”. From the negative result obtained at 140°C using a 10 cm sample cube, it was concluded that Octopamine hydrochloride is not a self-heating substance.
Key value for chemical safety assessment
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
