Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: QPRF Report
Title:
Acute oral toxicity ACD Percepta
Author:
Chemsafe S.r.l.
Year:
2019
Bibliographic source:
Sazonovas A, Japertas P & Didziapetris R (2012). Estimation of reliability of predictions and model applicability domain evaluation in the analysis of acute toxicity (LD50). SAR and QSAR in Environmental Research 21 (1), 127–148
Report date:
2019

Materials and methods

Principles of method if other than guideline:
Sazonovas A, Japertas P & Didziapetris R (2012). Estimation of reliability of predictions and model
applicability domain evaluation in the analysis of acute toxicity (LD50). SAR and QSAR in
Environmental Research 21 (1), 127–148

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyldiisopropylamine
EC Number:
230-392-0
EC Name:
Ethyldiisopropylamine
Cas Number:
7087-68-5
Molecular formula:
C8H19N
IUPAC Name:
ethylbis(propan-2-yl)amine
Test material form:
liquid

Results and discussion

Effect levels
Dose descriptor:
LD50
Remarks:
620 mg/Kg (mouse) 370 mg/kg (rat)
Remarks on result:
other:
Remarks:
QSAR predicted value

Applicant's summary and conclusion