2-aminoethanesulphonamide monohydrochloride

Guidance on Safe Use

First-aid measures

General information:
Immediately remove any clothing contaminated by the product. Move out of dangerous area. Consult a physician.
Inhalation: Move person to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Obtain medical aid.
Skin contact: Immediately flush skin with running water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Obtain medical aid immediately.
Eye contact: Immediately flush open eyes with running water for at least 15 minutes. Obtain medical aid immediately.
Ingestion: Do NOT induce vomiting without medical advice. Rinse mouth with water. Never administer anything by mouth to an unconscious person. Obtain medical aid immediately.

Fire-fighting measures

Suitable extinguishing media: Use water spray, dry chemical, carbon dioxide, or chemical foam.
Specific hazards arising from the chemical: Hydrogen chloride, Nitrogen oxides, Carbon oxides, Sulfuroxides
Advice for fire fighters: As in any fire, wear a NIOSH-approved or equivalent, pressure-demand, self-contained breathing apparatus and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion

Accidental release measures

Personal precautions, protective equipment and emergency procedures: Wear protective equipment and keep unprotected personnel away. Ensure adequate ventilation. Remove all sources of ignition. Prevent further leak or spill if safe to do so.

Environmental precautions: Do not let product enter drains, other waterways, or soil.
Methods and materials for containment and cleaning up: Prevent further leak or spill if safe to do so. Vacuum, sweep up, or absorb with inert material and place into a suitable disposal container. Consult local regulations for disposal.

Handling and storage

Precautions for safe handling: All work processes must always be designed so that the following is excluded: Inhalation of dust/particles , Skin contact , Eye contact . Provide adequate ventilation as well as local exhaustion at critical locations. Keep away from sources of ignition - No smoking. Only wear fitting, comfortable and clean protective clothing. Wash hands and face before breaks and after work and take a shower if necessary. Take precautionary measures against static discharges. When using do not eat, drink, smoke, sniff. Immediately remove any contaminated clothing, shoes or stockings. In the immediate working surroundings there must be : Emergency shower installed . Provide eye shower and label its location conspicuously .

Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a cool, well-ventilated place. Take precautionary measures against static discharges. Store in a place accessible by authorized persons only. Only use the material in places where open light, fire and other flammable sources can be kept away.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

Normal operation
Workers use PPE as a good practice to minimise possible exposures from minor accidental leaks during loading and unloading the reaction vessel, even though rigorous containment is ensured through technical means. Procedures are in place for disposal or cleaning of contaminated PPE.

Accident and incidents
A fully trained Emergency Response Team (ERT) is in place to react in case of accidents and incidents resulting in unexpected releases of the intermediate in order to minimize risks of exposures to humans and the environment. Components of the ERT are selected among senior site operators and technicians and are periodically trained and certified to respond to emergencies. Trainings and certifications of members ERT are subject to periodical revisions and approval by Local Fire Department. PPE as specified in emergency procedures and training are required in case of accidents and incidents. Procedures are in place for disposal or cleaning of contaminated PPE, as appropriate.

Maintenance and cleaning
Workers use additional PPE for cleaning the reaction vessel. A short exposure may occur during a maintenance operation, involving opening of a section of the pipeline connecting the reactor with loading station due to accidental presence of a residue of diluted intermediate that may lead to skin exposure. As a result, workers are given a specific work instruction on how to open this section, and are required to use high-efficiency PPE for skin and respiratory protection, as a precautionary and protective measure during all maintenance work, where there is a potential for exposure. PPE type is specified in the permit-to-work documents. Procedures are in place for disposal or cleaning of contaminated PPE, as appropriate.