sodium(S)-3-benzyloxycarbonylamino-2-methyl-4-oxo-azetidine-1-sulphonate

Guidance on Safe Use

First-aid measures

Emergency measure - Inhalation: Evacuate victim to fresh air and seek medical advice

immediately (show the label where possible).

Emergency measure - Eyes: Check and remove contact lenses. Immediately flush eyes with

cold running water for at least 15 minutes keeping eyelids

open. Seek immediate medical attention.

Emergency measure - Skin: Immediately flush skin  with cold running water for at least 15 minutes removing any contaminated clothing. Seek

immediate medical attention. Thoroughly launder and contaminated clothing before re-use.

Emergency measure - Ingestion: If ingested, seek medical advice immediately (show the label

where possible). DO NOT induce vomiting.

Fire-fighting measures

Recommended extinguishing agent: Small Fires: Use dry chemical powder.

Large Fires: Use water spray, fog or foam. Do not use water

water jet.

Product arising from burning: COx, NOx, SOx, HCl and Na.

Product determined by test: N

Protective equipment: Self-contained breathing apparatus and full protective

equipment are recommended.

Accidental release measures

Emergency measures in case of spillage: The affected area will be fenced or cordoned off and

individuals will not be allowed to touch or walk through the spilled material unless wearing appropriate protective

clothing. Dust generation will be avoided.

Suitable protective clothing will include gloves and

eye/face protection. As a minimum this will include: splash

goggles, disposable lab coat of low permeability with cuffs, double gloves, shoe covers, and an approved respirator.

Depending upon the nature of the spill (quantity and extent

of spill), additional protective clothing and equipment such

as self-contained breathing apparatus may be needed.

Spilled solids will be collected with a contained vacuum

unit or will be moistened and picked-up so as to minimise

dust generation. The substance will be placed in a suitable properly labelled container for recovery or disposal.

The cleaning will be finised by washing thoroughly with

detergent and water that will be disposed of according to

local and national requirements.

Handling and storage

Handling: The substance will be stored, handled, and used under

conditions of good industrial hygiene, and in conformity

with any local regulations in order to avoid exposure to the extent technically feasible.  Engineering controls in the

form of local exhaust ventilation and/or closed system

charging are recommended at the reactor.  When engineering controls are not sufficient to control dust exposure,

approved respiratory protection in conformance with EN136 will be worn.  For manufacturing areas, skin protection will

be provided in the form of overalls, or full air suits

along with impermeable gloves in conformance with EN368 and EN374, respectively. Rubber, neoprene or other gloves will

be required if solvents, corrosives or other chemicals are present.  Gloves will be changed regularly and removed after

overt contamination.  Chemical safety eye protection in

conformance with EN166 will be worn if a full-face

respirator is not worn.

Avoid dusting when handling and avoid all possible sources

of ignition (spark or flame). Specific areas will be

designated and restricted to persons trained and qualified

to work with these materials wearing appropriate PPE. A

designated area may encompass all or part of a laboratory,

e.g. a hood.

Storage: Storage will be in sturdy containers or unbreakable outer containers. Store at room temperature 25°C (77°F) or lower.

Store away from direct sunlight.

Eating, drinking etc are prohibited. Access is only to

authorised personnel, appropriately gowned and conforming to

local SOPs. Work clothing is not worn outside facility. All

staff are appropriately trained in safe working procedures

and provided with information on materials and processes.

Packaging of the substance and or preparation: UN approved fibre drums

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Air transport (UN RTDG/ICAO/IATA)

Shipping

Special provisions / remarks

Remarks:

Transport code: Not classified for transport
Transport: Not applicable

SpecialProvisions

Stability and reactivity

Danger other than fire: None known

Chemical reaction with water: None known

Dust explosion: Material exhibits explosion characteristics if ignited as a

dust cloud. Material is susceptible to accumulating static

charges during processing. Provide suitable bonding and grounding for containers and process equipment to control

static charge. Powder handling equipment such as dust

collectors, dryers, and mills may require additional

protective measures (e.g. explosive venting).

Dust explosion determined by test: Y

Disposal considerations

Industry - Possibility of recovery/recycling: Discharge to the environment will be minimal. Trace

quantities are destroyed by biological oxidation in

wastewater treatment plants.  Recovery of larger spillages of uncontaminated material for subsequent use is

recommended. As material is used in the process, no recycling of material is possible.

Industry - Possibility of neutralisation: No method of neutralization is known.

Industry - Possibility of destruction: controlled discharge: Trace quantities are destroyed by biological oxidation in

wastewater treatment plants.

Industry - Possibility of destruction - incineration: Incineration is recommended for larger quantities.  A

closed-cycle incinerator with scrubbers should be employed.

National and local regulations must be observed.

Industry - Possibility of destruction - water purification: The substance should not normally be discharged directly to

the sewage system or aqueous environment.  However, there

are unlikely to be adverse effects on sewage treatment

systems, because the substance has been shown not to be

unduly toxic to sewage microorganisms.  Therefore trace quantities can be treated in a secondary biological WWTP

before discharge to municipal works.

Industry - Possibility of destruction - other: None known.

Public at large - Possibility of recovery/recycling: The substance will not enter the public domain.

Public at large - Possibility of neutralisation: The substance will not enter the public domain.

Public at large - Possibility of destruction: controlled discharge: The substance will not enter the public domain.

Public at large - Possibility of destruction - incineration: The substance will not enter the public domain.

Public at large - Possibility of destruction - water purification: The substance will not enter the public domain.

Public at large - Possibility of destruction - others: The substance will not enter the public domain.