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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 5 July 2017 to 13 July 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
equivalent or similar to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
GLP compliance:
not specified
Other quality assurance:
ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
Type of method:
Laser scattering/diffraction
Type of particle tested:
primary particle
Type of distribution:
volumetric distribution
Specific details on test material used for the study:
SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 17025 25/26/28
- Expiration date of the lot/batch:13 May 2020
- Manufacturing date: 13 may 2017
Strontium diacetate used as test item is hemihydrated
Mass median aerodynamic diameter:
72 µm
Percentile:
D10
Mean:
15.81 µm
St. dev.:
47.22
Percentile:
D50
Mean:
72.16 µm
St. dev.:
47.22
Percentile:
D90
Mean:
142.8 mm
St. dev.:
47.22
No.:
#1
Size:
0 µm
Distribution:
0 %
No.:
#2
Size:
10 µm
Distribution:
6.63 %
No.:
#3
Size:
20 µm
Distribution:
12.4 %
No.:
#4
Size:
25 µm
Distribution:
15.4 %
No.:
#5
Size:
32 µm
Distribution:
19.8 %
No.:
#6
Size:
50 µm
Distribution:
32.9 %
No.:
#7
Size:
63 µm
Distribution:
43 %
No.:
#8
Size:
71 µm
Distribution:
49.1 %
No.:
#9
Size:
75 µm
Distribution:
52.1 %
No.:
#10
Size:
90 µm
Distribution:
63 %
No.:
#10
Size:
100 µm
Distribution:
69.6 %
Conclusions:
The median particle size D50 of the test item deduced from the particle size distributions was : 72.16 micrometer.
The particle size D10 of the test item deduced from the particle sizedistributions was :15.81 micrometer.
The particle size D90 of the test item deduced from the particle size distributions was : 142.8 micrometer.
Executive summary:

The particle size distribution of strontium diacetate was determined following ISO 13320 (Particle size analysis - Laser diffraction methods).

The particle size distributions were determined in a test serie. For the test serie fraction (left axis of the ordinate) and the shiftings (right axis of the ordinate) are presented in percent by volume as a function

of the particle size. Median value was calculated from unrounded values.

The median particle size D50 of the test item deduced from the particle size distributions was : 72.16 micrometer.

The particle size D10 of the test item deduced from the particle size distributions was : 15.81 micrometer.

The particle size D90 of the test item deduced from the particle size distributions was : 142.8 micrometer.

Description of key information

The particle size distribution of strontium diacetate was determined following ISO 13320 (Particle size analysis - Laser diffraction methods).

The particle size distributions were determined in a test serie. For the test serie fraction (left axis of the ordinate) and the shiftings (right axis of the ordinate) are presented in percent by volume as a function of the particle size. Median value was calculated from unrounded values.

The median particle size D50 of the test item deduced from the particle size distributions was : 72.16 micrometer.

The particle size D10 of the test item deduced from the particle size distributions was : 15.81 micrometer.

The particle size D90 of the test item deduced from the particle size distributions was : 142.8 micrometer.

Additional information