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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: inhalation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because exposure of humans via inhalation is not likely taking into account the vapour pressure of the substance and/or the possibility of exposure to aerosols, particles or droplets of an inhalable size
Cross-reference
Reason / purpose for cross-reference:
data waiving: supporting information
Reference
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
03 October - 05 December, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Version / remarks:
23rd March 2006
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.4 (Vapour Pressure)
Version / remarks:
August 24, 2009
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
effusion method: Knudsen cell
Key result
Test no.:
#1
Temp.:
20 °C
Remarks on result:
other: 20 °C: 2.650 x 10-8 Pa
Key result
Test no.:
#2
Temp.:
25 °C
Remarks on result:
other: 25 °C: 5.899 x 10-8 Pa

The vapour pressure was measured in the temperature range of 140 to 168 °C. For the evaluation the vapour pressure values in the range of 144 to 168 °C were used. The measured vapour pressure values together with the measured temperatures are listed in Table

Results of the Effusion method

Stage No.

Temperature, °C

¿m/¿t, mg/min

Vapour pressure, Pa

1

144.0

2.0962 x 10-4

4.1865 x 10-2

2

148.0

2.5814 x 10-4

5.1802 x 10-2

3

152.0

3.2701 x 10-4

6.5934 x 10-2

4

156.0

4.5342 x 10-4

9.1849 x 10-2

5

160.0

6.4018 x 10-4

1.3029 x 10-1

6

164.0

9.2700 x 10-4

1.8953 x 10-1

7

168.0

1.1712 x 10-3

2.4054 x 10-1

 

The vapour pressure of the test item p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20 and 25 °C:

 

Vapour pressure of

p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 20 °C:2.650 x 10-8Pa

Vapour pressure of

p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 25 °C:5.899 x 10-8Pa

 

Conclusions:
The vapour pressure of the test item p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) was calculated by extrapolation of the measured vapour pressure curve for the temperatures 20 and 25 °C:

Vapour pressure of
p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 20 °C: 2.650 x 10-8 Pa
Vapour pressure of
p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 25 °C: 5.899 x 10-8 Pa
Executive summary:

Vapour pressure of p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) was determined using Vapor Pressure Analyzer (Knudsen Effusion Method).

The following result was obtained:

Vapour pressure of p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 20 °C:2.650 x 10-8Pa Vapour pressure of p-Nitrobenzoic acid, compound with 2,2’,2”-nitrilotriethanol (1:1) at 25 °C:5.899 x 10-8Pa.

 

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion