Registration Dossier
Registration Dossier
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EC number: 244-759-8 | CAS number: 22071-15-4
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1984
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Pharmacological properties of 2-[4-(2-thiazolyloxy)-phenyl]-propionic acid (480156-S), a new non-steroidal antiinflammatory agent.
- Author:
- Hirose K, Jyoyama H, Kojima Y, Eigyo M, Hatakeyama H, Asanuma F, Umehara H, Yamaguchi T.
- Year:
- 1 984
- Bibliographic source:
- ChemID Data Source
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Ketoprofen
- EC Number:
- 244-759-8
- EC Name:
- Ketoprofen
- Cas Number:
- 22071-15-4
- Molecular formula:
- C16H14O3
- IUPAC Name:
- 2-(3-benzoylphenyl)propanoic acid
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 62.4 mg/kg bw
Applicant's summary and conclusion
- Conclusions:
- LD50 (oral) rat: 62400ug/kg (62.4mg/kg)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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