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EC number: 260-152-0 | CAS number: 56396-10-2
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- The study was conducted between 13 September 2000 and 7 December 2000.
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- Version / remarks:
- (draft)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Specific details on test material used for the study:
- Identity: ST463.
Appearance: magenta powder
Storage conditions: room temperature
Batch number: 6558
Expiry date: August 2001
Purity: 99.4%
Date received: 1 August 2000 - Radiolabelling:
- no
- Test temperature:
- 30°C
- Details on study design: HPLC method:
- Procedure:
As the test substance is ionisable, the test was conducted at both pH 4 and pH 10 thus covering the range of environmentally significant pH values. The pH 4 test was conducted as follows:
In order to correlate the measured capacity factor (k) of the test material with its Koc, six reference materials were selected from a list of recommended compounds. These reference compounds were selected to have a log10Koc values between 1.4 and 5.4. An internal standard (formamide) with no retention on the HPLC column was used to determine the deadtime for the HPLC system. THe following reference mixture was prepared in HPLC mobile phase.
Reference substance Known log10Koc Concentration (mg/L)
I.D.S Deadtime only 6220
Phenol 1.43 486
Nitrobenzene 2.36 116
Naphthalene 3.04 108
2-Methylnapthalene 3.87 112
Anthracene 4.41 7.17
DDT 5.38 34.9
A solution of test substance (10.07 mg/l in demethyl sulpoxide:methanol (1:1 v/v)) was prepared and chromatographed in duplicate, bracketed by samples of the reference mixture, using the following conditions:
HPLC conditions:
Instrument: Hewlett Packard 1050 Liquid Chromatograph
Column: Hypersil 5 µm CPS (25 cm x 4.6 mm internal diameter)
Column temperature: 30°C
Mobile phase compostion: Methanol:pH 4 buffer (55:45 v/v)
Flow rate: 1 ml/min
Injection volume: 25 µm
Detector: UV set at 210 nm (reference mixture); UV set at 516 nm (test substance)
Internal deadtime standard (I.D.S): Formamide
pH 10 test:
The pH 10 test was conducted identically, with the exception that the mobile phase employed was methanol:pH 10 buffer (55:45 v/v).
The adsorption coefficient is deduced from the capacity factor (k) give by:
k = tr - t0 / t0
where:
tr is the measured time of sample of reference
t0 is the retention time of the internal deadtime standard. - Sample No.:
- #1
- Type:
- log Koc
- Value:
- > 5.4 dimensionless
- pH:
- 4
- Temp.:
- 30 °C
- Sample No.:
- #2
- Type:
- log Koc
- Value:
- > 5.4 dimensionless
- pH:
- 10
- Temp.:
- 30 °C
- Details on results (HPLC method):
- pH 4 test:
The reference standards eluted in order of their log10Koc values. The test substance was longer retained than any of the reference standards and therefore has a log10Koc value of greater than 5.4.
pH 10 test:
As a pH 4, the test substance was found to have a log10Koc value of greater than 5.4. - Validity criteria fulfilled:
- not applicable
- Conclusions:
- The test substance was found to have a log10Koc value of >5.4.
- Executive summary:
The adsorption coefficient of the substance was determined using the HPLC method. The study was conducted to OECD guideline 121.
The test substance was found to have a log10Koc value of >5.4.
Reference
Description of key information
The adsorption coefficient of the substance was determined using the HPLC method. The study was conducted to OECD guideline 121.
The test substance was found to have a log10Kocvalue of >5.4.
Key value for chemical safety assessment
- Koc at 20 °C:
- 251 189
Additional information
[LogKoc: 5.4]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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