Registration Dossier
Registration Dossier
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EC number: 249-740-8 | CAS number: 29636-87-1
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: tabular literature information
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 010
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 5-methyl-1H-imidazole-4-methanol
- EC Number:
- 249-740-8
- EC Name:
- 5-methyl-1H-imidazole-4-methanol
- Cas Number:
- 29636-87-1
- Molecular formula:
- C5H8N2O
- IUPAC Name:
- (4-methyl-1H-imidazol-5-yl)methanol
- Details on test material:
- provided by GlaxoSmithKline or from comercial supplier
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
- Details on test animals or tissues and environmental conditions:
- no dat
Test system
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- no data
- Duration of treatment / exposure:
- no data
- Observation period (in vivo):
- no data
- Number of animals or in vitro replicates:
- no data
- Details on study design:
- no data
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- other: GHS Cat 2
- Remarks:
- Criteria used for interpretation of results: OECD GHS
- Conclusions:
- Causes serious eye irritation
- Executive summary:
Causes serious eye irritation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
