Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: EEC Directive 92/69, B.3.
GLP compliance:
yes
Limit test:
yes

Test material

Constituent 1

Test animals

Species:
other: HanRcc:WIST (SPF) rats

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
other: Desiccated corn oil.
Duration of exposure:
24 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
Signs of toxicity related to dose levels:
No systemic signs of toxixity were observed during the study
period.

The body weights of the animals were in the normal range for
this strain and age.
Gross pathology:
Effects on organs:
No macroscopic findinds were observed at necropsy.
Other findings:
Signs of toxicity (local):
Slight general erythema was noted in all males up to the
eigth day. Slight crust formation and slight scaling were in
three males up to the fifteenth and twelveth day,
respectively.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU