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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: inherent biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2007
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report date:
2007

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 302 B (Inherent biodegradability: Zahn-Wellens/EMPA Test)
GLP compliance:
not specified

Test material

1
Chemical structure
Reference substance name:
5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one monohydrochloride
EC Number:
812-545-9
Cas Number:
93173-05-8
Molecular formula:
C19H21N5O2 x HCl
IUPAC Name:
5,11-dihydro-11-((4-methyl-1-piperazinyl)acetyl)-6H-pyrido(2,3-b)(1,4)benzodiazepin-6-one monohydrochloride
Test material form:
solid: bulk

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
other: Factor X (used in the DBO5) prepared in the laboratory
Duration of test (contact time):
28 d

Results and discussion

% Degradation
Parameter:
other: DQO (mg/l O2)
Value:
7.2
Sampling time:
28 d

Applicant's summary and conclusion

Interpretation of results:
not readily biodegradable
Conclusions:
NON BIODEGRADABLE PRODUCT (7,2 %)