Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Genetic toxicity: in vitro

Currently viewing:

Administrative data

Endpoint:
in vitro gene mutation study in bacteria
Remarks:
Type of genotoxicity: gene mutation
Type of information:
not specified
Adequacy of study:
supporting study
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Taken from company MSDS, original data not located.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
1997

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
Ames test
Type of assay:
bacterial reverse mutation assay

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(trichlorovinyl)anilinium chloride
EC Number:
279-862-7
EC Name:
3-(trichlorovinyl)anilinium chloride
Cas Number:
81972-27-2
Molecular formula:
C8H6Cl3N.ClH
IUPAC Name:
3-(1,2,2-trichloroethenyl)anilinium chloride
Test material form:
not specified

Method

Species / strain
Species / strain / cell type:
not specified
Additional strain / cell type characteristics:
not specified
Metabolic activation:
not specified

Results and discussion

Test results
Species / strain:
not specified
Metabolic activation:
not specified
Genotoxicity:
negative
Cytotoxicity / choice of top concentrations:
not specified
Vehicle controls validity:
not specified
Untreated negative controls validity:
not specified
Positive controls validity:
not specified
Remarks on result:
other: all strains/cell types tested
Remarks:
Migrated from field 'Test system'.

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information):
negative no further details available
Executive summary:

Statement on original MSDS 'Negative in the Ames bacterial mutagenicity test'.