Registration Dossier
Registration Dossier
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EC number: 209-923-5 | CAS number: 598-21-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 for freshwater algae is < 1 mg/l
Key value for chemical safety assessment
Additional information
As usual for an acid halide, bromoacetyl bromide hydrolyzes rapidly in water, forming bromoacetic acid and hydrobromic acid. Therfore, aquatic toxicity data for bromoacetic acid sufficiently provides information for the toxicity of bromoacetyl bromide as well. For bromoacetic acid a QSAR model is used to predict algae toxicity.
Although the model has significant limitations due to the low number of compounds included, the model performs well for the structural class of haloacids. Other haloacids like Chloroacetic acid or Fluoroacetic acid have predicted EC50 values below 1 mg/l which fit well to the experimental EC50 values supporting that the QSAR works well for haloacids (experimental data for Chloroacetic acid or Bromoacetic acid => see the respective Reach dossiers).
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