Calcium dihydroxide

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

migrated information: read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study with acceptable restrictions

Data source

Reference

Reference 1

Reference Type:

publication

Title:

Statistical models to predict the toxicity of major ions to Ceriodaphnia dubia, Daphnia magna and Pimephales promelas (fathead minnows).

Author:

Mount DR et al.

Year:

1997

Bibliographic source:

Env Toxicol Chem 16(10): 2009-2019

Reference 2

Reference Type:

secondary source

Title:

SIDS Initial Assessment Report, Calcium chloride, CAS: 10043-52-4

Author:

OECD

Year:

2002

Bibliographic source:

UNEP publications

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: EPA/600/4-90/027, EPA/600/6-91/003

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Calcium chloride

EC Number:

233-140-8

EC Name:

Calcium chloride

Cas Number:

10043-52-4

IUPAC Name:

calcium dichloride

Details on test material:

- Name of test material: Calcium dichloride

Sampling and analysis

Analytical monitoring:

yes

Test solutions

Vehicle:

no

Test organisms

Test organisms (species):

Pimephales promelas

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Reference substance (positive control):

not specified

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

4 630 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Remarks:

Calcium chloride, CAS: 10043-52-4

Basis for effect:

mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:

- Test Organisms:

a) Size: Not described

b) Age: 1-7 days old

c) Pretreatment: no data

d) Supplier/Source: ENSR, Fort Collins, CO,

- Test Conditions:

a) Dilution Water Source: moderately hard reconstituted water (MHRW)

b) Exposure Vessel Type: 30ml plastic beaker

c) Nominal Concentrations: 10,000, 5,000, 2,500, 1,250

mg/l

d) Stock Solutions Preparations and Stability: 10,000mg/l

in MHRW

e) Number of Replicates: 2-5

f) Individuals per Replicates: 5

g) Renewal Rate of Test Water: not renewed

h) Water Temperature: 25 °C

i) Light Condition: 16:8h(light:dark)

j) Feeding: concentrated brine shrimp nauplii was added after 48h of

exposure.

- Method of Analytical Monitoring: using ICP according to USEPA method

200.7

- Statistical Method:

a) Data Analysis: Spearman-Karber method