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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation / corrosion, other
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2014
Report date:
2014

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 439 (In Vitro Skin Irritation: Reconstructed Human Epidermis Test Method)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[(4-acetylnaphthalen-1-yl)formamido]-N-(2,2,2-trifluoroethyl)acetamide
EC Number:
807-880-2
Cas Number:
1125812-54-5
Molecular formula:
C17H15F3N2O3
IUPAC Name:
2-[(4-acetylnaphthalen-1-yl)formamido]-N-(2,2,2-trifluoroethyl)acetamide

Results and discussion

In vitro

Results
Irritation / corrosion parameter:
other: Score
Value:
ca. 0

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The MR-008-4 intermediate is non corrosive and non-irritant for the skin