Registration Dossier
Registration Dossier
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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 942-932-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Short-term toxicity to fish Fish:
In this 96-hour semi-static acute toxicity test on Zebrafish (Brachydanio rerio) the test item Methyl-isobutyl-ketone-peroxide (MIKP) had significant toxic effects on fish. The 96-h LC50 value was determined to be 1.89 mg/L. The 96-h NOEC and LOEC values were determined to be 1.38 mg/L and 2.62 mg/L, respectively. The results are based on measured test item concentrations.
Short-term toxicity to aquatic invertebrates:
In this 48-hour acute toxicity test on Daphnia magna, the obtained results showed that the test item Methyl-isobutyl-ketone-peroxide (MIKP) had significant toxic effects on the mobility of Daphnia. The 48-h EC50 value was determined to be 4.48 mg/L. The 48-h NOEC was determined to be 2.00 mg/L and the 48-h LOEC was determined to be 5.11 mg/L. The results are based on measured test item concentrations.
Toxicity to aquatic algae
In an algal growth inhibition test with Raphidocelis subcapitata, the 72-h EC10, EC20, EC50 for growth rate for MIKP were determined to be 0.94, 1.07 and 1.33 mg/L, respectively. The 72-h EC10, EC20, EC50 for yield were determined to be 0.65, 0.78 and 1.04 mg/L, respectively. The LOEC values based on growth rate and yield were determined to be 1.04 mg/L. The 72-h NOEC for growth rate and yield was determined to be 0.15 mg/L. The results are based on measured geometric mean test item concentrations.
Toxicity to microorganisms:
Under the conditions of the performed Activated Sludge Respiration Inhibition Test, the EC10 and EC50 values of test item were determined as 12.8 mg/L (95% confidence limits: 10.5–15.6 mg/L) and 37.0 mg/L (95% confidence limits: 32.4–42.2 mg/L), respectively. Based on the statistical and biological evaluation in this test the NOEC was determined as 6.33 mg/L.
Long-term toxicity testing to fish and aquatic invertebrates was waived based on ready biodegrability and very limited exposure to the environment, if any.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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