Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 288-107-0 | CAS number: 85650-96-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Pigment additive Kr 1789 Stck. Ber. 100% (CAS 85650-96-0): There is a high probability that the product is not acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Additional information
The Pigment additive Kr 1789 Stck. Ber. 100% (CAS 85650-96-0) is composed of Copper phthalocyanine monosulfonic acid (CAS 28901-96-4) and oleylamine (CAS 112-90-3).
The key study on acute toxicity of the target item Pigment additive Kr 1789 to Daphnia magna has been conducted according to OECD 202 following a semi-static test system setup (BASF SE 2017). At test termination after 48 h an "Effective Loading Rate" > 100 mg/L (nominal) was determined. No effects were observed up to the highest loading rate.
For the constituents Copper phthalocyanine monosulfonic acid (CAS 28901-96-4) and oleylamine (CAS 112-90-3) supporting studies are available.
For the pigment compound Copper phthalocyanine monosulfonic acid (CAS 28901-96-4) the assessment is based on toxicity data on Daphnia magna, as well as on read-across data for the structural analogous substance copper phthalocyanine (CAS 147-14-8). Daphnids (Daphnia magna) were exposed in a GLP guideline study according to OECD 202 for 48 hours. The effect of CAS 59160-79-1 on the swimming behavior was investigated; 48-h EC50 value of > 100 mg/l (nominal) were determined (ibacon, 2015). Supporting this, the structural analogue CAS 147-14-8 was investigated in several studies regarding toxicity in aquatic invertebrates. One study comparable to OECD TG 202 revealed an EC50 > 500 mg/L (BASF AG 1989). BASF AG (2001) showed EC 50 > 100 mg/L in a screening study according EED Directive 93/32/EWG. Finally, a screening test according to EEC Directive 93/32/EEC confirmed these findings with an EC50 > 100 mg/L (nominal; BASF AG 2004).
In summary, Copper phthalocyanine (CAS 147-14-8) is concluded to be with high probability not harmful to aquatic invertebrates.
Further supporting study on the toxicity of oleylamine (CAS 112 -90 -3) to aquatic invertebrates was assessed in a study according to OECD TG 202 under static conditions. Daphnia magna was used as test species. The test concentrations were analytically verified. A 48 -h EC50 was determined to be 0.011 mg/L (nominal; Mark et al., 1995).
It can be concluded that oleylamine is acutely very toxic to aquatic invertebrates.
In conclusion Pigment additive Kr 1789 is not acutely harmful for aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
