Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
other: Exposure estimation
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)

Data source

Reference
Title:
No information
Author:
Pennington JAT (1991). Silicon in foods and diets. Food Add.|and Cont. 8(1), 97-118.

Materials and methods

Type of study / information:
Type of experience: Human - Exposure through Food
Principles of method if other than guideline:
Exposure estimation

Test material

Constituent 1
Chemical structure
Reference substance name:
Silicic acid, potassium salt
EC Number:
215-199-1
EC Name:
Silicic acid, potassium salt
Cas Number:
1312-76-1
Molecular formula:
K2O x (SiO2)n with Molar Ratio (MR) (SiO2/K2O): 0.5 – 5 (with exception of MR = 1)
IUPAC Name:
potassium hydroxysilanoylolate

Method

Exposure assessment:
estimated

Results and discussion

Any other information on results incl. tables

The average intake of silicon is 20-50 mg total Si/d (Pennington, 1991). An estimation of 0.31 mg Si/kg bw/d in
females and 0.53 mg Si/kg bw/d in males made in an American study, is representative for the intake in the Western
world. While the highest concentrations of total silicon are found in seafood, eggs and diary products; the main dietary
sources are cereals and beverages.

Applicant's summary and conclusion