Registration Dossier
Registration Dossier
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EC number: 204-658-1 | CAS number: 123-86-4
Toxicity to terrestrial plants
Administrative data
Link to relevant study record(s)
Description of key information
Lactuca sativa 14-day EC50 > 1000 mg/kg soil dry weight (similar to OECD TG 208; Hulzebos et al., 1993)
Key value for chemical safety assessment
Additional information
The effects of n-butyl acetate on growth of lettuce (Lactuca sativa) seedlings were investigated in a study conducted similarly to OECD TG 208. After 7 and 14 days their fresh weight was determined. Test concentrations were verified by chemical analysis. Based on nominal concentrations, the 7 -d and 14 -d EC50 was greater than 1000 mg/kg dw (Hulzebos et al., 1993).
No long-term test data are available.
In accordance with REACH Annex IX and X, 9.4, Column 2, the EPM method may be applied to assess the hazard for soil organisms and long-term toxicity testing shall only be proposed by the registrant if the results of the CSA indicate the need to investigate further the effects of the substance and/or degradation products on terrestrial organisms.As the substance is ready biodegradable, not assumed to be highly adsorptive to soil (log Kow < 3, no other indications of high adsorption), and of low aquatic toxicity (EC/LC50 > 1 mg/L) the substance was assigned to soil hazard category 1, according to the ITS as described in ECHA Guidance on Information Requirements and CSA, R.7c. Applying the EPM method to assess the hazard for soil organisms no risks were identified and in conclusion soil toxicity testing is not required.
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