Registration Dossier
Registration Dossier
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EC number: 200-835-2 | CAS number: 75-05-8
Biodegradation in water and sediment: simulation tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: sewage treatment simulation testing
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- documentation insufficient for assessment
- Remarks:
- Limited information available. Not a widely recognized data source
- Principles of method if other than guideline:
- No information available.
- GLP compliance:
- no
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, adapted
- Initial conc.:
- 139 mg/L
- Based on:
- test mat.
- Details on study design:
- - Test temperature: 22 to 25 deg C
- % Degr.:
- > 98
- Parameter:
- other: oxygen demand
- Sampling time:
- 28 d
- % Degr.:
- > 70
- Parameter:
- other: theoritical oxidation
- Sampling time:
- 28 d
- Executive summary:
Following 28 -day acclimation, Ludzack (1960) reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 degrees C. Removal of acetonitrile was based on the difference between the influent and effluent oxygen demands. Theoretical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.
- Endpoint:
- biodegradation in water: sediment simulation testing
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is readily biodegradable
- Endpoint:
- biodegradation in water: simulation testing on ultimate degradation in surface water
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is readily biodegradable
Referenceopen allclose all
Following 28 days acclimation acetonitrile was introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 degree C. Degradation (>98% removal) was based on the difference between the influent and effluent oxygen demands, while theortetical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.
Description of key information
Early tests reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal. A waiver from further simulation testing in water and sediment is requested.
Key value for chemical safety assessment
Additional information
Following 28 -day acclimation, Ludzack (1960) reported >98% removal of acetonitrile introduced to activated sludge as a continuous feed with effluent removal. The study was conducted at 22-25 °C. Removal of acetonitrile was based on the difference between the influent and effluent oxygen demands. Theoretical oxidation (>70%) was based on the ratio of observed oxygen demand and theoretical oxygen demand.
A waiver from further simulation testing in water and sediment is requested on the basis of this early study and the fact that acetonitrile is readily biodegradable in reliable screening tests.
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