Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
biochemical or cellular interactions
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Unsuitable test system; the main focus of the publication is 3,3´-diaminobenzidine, in the frame of further investigations by benzidine derivatives 4-ADPA was tested

Data source

Reference
Reference Type:
publication
Title:
Mitochondrial oxidation of 3,3'-diaminobenzidine and related compounds, and their possible realtion to carcinogenesis.
Author:
Hirai K and Yasuhira K
Year:
1972
Bibliographic source:
GANN 63, 665 - 673

Materials and methods

Principles of method if other than guideline:
other: biochemical test
GLP compliance:
not specified
Type of method:
in vitro
Endpoint addressed:
not applicable

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(4-aminophenyl)aniline
EC Number:
202-951-9
EC Name:
N-(4-aminophenyl)aniline
Cas Number:
101-54-2
Molecular formula:
C12H12N2
IUPAC Name:
N1-phenylbenzene-1,4-diamine
Details on test material:
TS-Freetext:
no data

Results and discussion

Any other information on results incl. tables

RS-Freetext:

Applicant's summary and conclusion