Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-764-2 | CAS number: 99-54-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment
Data source
Reference
- Reference Type:
- publication
- Title:
- Hygienic standard for 3,4-dichloronitrobenzene vapor in the air of working premises.
- Author:
- Belyaev VA and Kuznetsov AV
- Year:
- 1 969
- Bibliographic source:
- Hyg Sanit 34: 211 - 214
Materials and methods
- Principles of method if other than guideline:
- Method: other: no data
- GLP compliance:
- no
- Test type:
- other: migrated dataset
Test material
- Reference substance name:
- m-cresol
- EC Number:
- 203-577-9
- EC Name:
- m-cresol
- Cas Number:
- 108-39-4
- Molecular formula:
- C7H8O
- IUPAC Name:
- 3-Methylphenol
- Details on test material:
- no data on purity
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: albino
- Sex:
- not specified
Administration / exposure
- Route of administration:
- other: migrated dataset
- Type of inhalation exposure:
- other: migrated dataset
- Vehicle:
- other: migrated dataset
- Duration of exposure:
- 4 h
- Concentrations:
- 3, 6 or 10 mg/m³
- No. of animals per sex per dose:
- 40
- Control animals:
- other: migrated dataset
Results and discussion
Any other information on results incl. tables
RS-Freetext:
<= 6 mg/m³: no adverse effects were reported
10 mg/m³: no "external" signs of intoxication; increased
number of Heinz bodies and reticulocytes and decreased
activity (13 % lower) of blood peroxidase 24 hrs after
exposure
Applicant's summary and conclusion
- Executive summary:
migrated dataset
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
