Registration Dossier
Registration Dossier
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EC number: 231-293-5 | CAS number: 7486-38-6
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
Results from the corresponding acid of disodium adipate are taken into account for this endpoint. A BCF of 3.162 is estimated using the EPI Suite program, v.3.20for adipic acid. This value is in good agreement with the calculated log Kow values for the dissociated and non-dissociated form of disodium adipate.
Key value for chemical safety assessment
- BCF (aquatic species):
- 3.162 dimensionless
Additional information
Measured bioconcentration factors (BCF) obtained in bioaccumulation
studies for disodium adipate and its corresponding acid, adipic acid are
not available. A read-across
approach with adipic acid is applied. In aqueous media, disodium adipate
and adipic acid acid dissociate into the corresponding anion
(1,6-hexandioic acid ion) and the sodium ion and hydrogen ion (proton),
respectively. Fate, behavior and the ecotoxicological properties of
adipic acid and its disodium salt are thought to be an effect of the
di-carboxylate ion rather than of the sodium ion or the hydrogen ion
(proton), which are normal constituents in environmental systems and
have no relevant ecotoxic properties in low concentrations.
Therefore a read-across between disodium adipate and adipic acid is
justified.
From the octanol-water partition coefficient a bioconcentration factor (BCF) can be calculated with the BCF Program.
Based on the standard formula for ionic compounds having a log Kow lower than 5, a BCF of 3.162 is estimated
indicating a very low potential for bioaccumulation of adipic acid in aquatic organisms.This value is in good agreement with the calculated log Kow values for the dissociated and non-dissociated form of disodium adipate.
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