Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 938-647-4 | CAS number: 942288-39-3
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- publication
- Title:
- A Hierarchical Clustering Methodology for the Estimation of Toxicity
- Author:
- Todd Martin, Paul Harten, Raghuraman Venkatapathy, and Douglas Young
- Year:
- 2 008
- Bibliographic source:
- Toxicology Mechanisms and Methods 18:251–266.
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: REACH guidance on QSARs R.6, May/July 2008
Test material
- Reference substance name:
- (2R,3R,5R)-4,4-difluoro-2-[(3-fluorobenzoyloxy)methyl]-5-(methanesulfonyloxy)oxolan-3-yl 3-fluorobenzoate; (2R,3R,5S)-4,4-difluoro-2-[(3-fluorobenzoyloxy)methyl]-5-(methanesulfonyloxy)oxolan-3-yl 3-fluorobenzoate
- EC Number:
- 938-647-4
- Cas Number:
- 942288-39-3
- Molecular formula:
- C20H16F4O8S
- IUPAC Name:
- (2R,3R,5R)-4,4-difluoro-2-[(3-fluorobenzoyloxy)methyl]-5-(methanesulfonyloxy)oxolan-3-yl 3-fluorobenzoate; (2R,3R,5S)-4,4-difluoro-2-[(3-fluorobenzoyloxy)methyl]-5-(methanesulfonyloxy)oxolan-3-yl 3-fluorobenzoate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 1 075.28 mg/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
