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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: oral

Currently viewing:

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Basic data given Limited information concerning test conditions and/or experimental methods

Data source

Referenceopen allclose all

Reference Type:
study report
Title:
Unnamed
Year:
1970
Reference Type:
study report
Title:
Unnamed
Year:
1999
Reference Type:
secondary source
Title:
SIDS Category of Alkyl sulfates, Alkane sulfonates and Alpha-olefin sulfonates
Author:
OECD
Year:
2007
Bibliographic source:
UNEP Publications

Materials and methods

Principles of method if other than guideline:
Method: other
GLP compliance:
no
Limit test:
no

Test material

Constituent 1
Reference substance name:
85665-45-8 (purity 46-49%)
IUPAC Name:
85665-45-8 (purity 46-49%)
Details on test material:
Purity:
46-49 % active substance, balance being water

Chain Length Distribution:
C8: 8.5%
C10: 8.5%
C12: 68%
C14: 25%
C16: 6%

Test animals

Species:
rat
Strain:
Wistar
Sex:
male

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
not specified
Doses:
single application of increasing doses (not further specified)
No. of animals per sex per dose:
10

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 3 625 mg/kg bw
Based on:
act. ingr.

Any other information on results incl. tables

LD50 given with 7.94 mL/kg

CLINICAL SIGNS: abdominal position, decreased motility, apathy

NECROPSY FINDINGS: no data

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU