Registration Dossier
Registration Dossier
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EC number: 247-426-5 | CAS number: 26040-51-7
Endpoint summary
Administrative data
Description of key information
Additional information
Stability
The substance is hydrolytically unstable showing half-life-times at 50°C of 30.39 h at pH 4, 44.08 h at pH 7 and 77.52 h at pH 9. One transformation product was identified as tetrabromophthalic acid.
Biodegradation (screening tests)
According to OECD Guideline 302C (Inherent Biodegradability: Modified MITI Test (II)) a degradation of 7 % after 28 days was observed. In conclusion the substance is not inherently biodegradable and as a conclusion no ready biodegradability is assumed.
Biodegradation (water/sediment, soil)
The substance is considered as not inherently biodegradable. There is no indication that better biodegradability will be observed in the water/sediment and soil compartment. Therefore, performance of a study in water/sediment and soil does not appear scientifically necessary.
Adsorption/desorption
Following the OECD Guideline 121 (HPLC method) a logKoc value of 7.3 was received. This value indicates that the substance has a very strong sorption potential to soil and sediment and a negligible migration potential to groundwater.
Bioaccumulation
The study to determine the BMF of bis(2-ethylhexyl) tetrabromophthalate (TBPH) was conducted according to OECD guideline 305. After 28 days for uptake, and another 28 days for depuration a kinetic BMFk of 0.004 was determined subsequently, which was corrected for growth dilution effects resulting in a BMFkg of 0.014. Finally, a lipid-correction of the BMF was conducted, in order to standardize the BMF for comparative analyses of the results. The resulting BMFkgL of 0.038 indicates that TBPH is not bioaccumulative to fish of the species Oncorhynchus mykiss when applied orally and uptake results via the digestive tract. The critical threshold for classification of substances to be bioaccumulative are BMF values >1 as suggested in the guidance document of the European commission for delivering environmental standards.
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