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EC number: 421-320-0 | CAS number: 118289-55-7 CP-89,575
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 8th August 1997 to 17th October 1997
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 997
- Report date:
- 7997
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- GLP compliance:
- yes
- Type of distribution:
- other: Coulter Counter
Test material
- Reference substance name:
- 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one
- EC Number:
- 421-320-0
- EC Name:
- 6-chloro-5-(2-chloroethyl)-1,3-dihydroindol-2-one
- Cas Number:
- 118289-55-7
- Molecular formula:
- Hill formula: C10 H9 Cl2 N O CAS formula: C10 H9 Cl2 N O
- IUPAC Name:
- 6-chloro-5-(2-chloroethyl)-2,3-dihydro-1H-indol-2-one
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Expiry date: 2 June 1999
Purity: 98.82% by HPLC
Date received: 2 June 1997
Constituent 1
Results and discussion
- Mass median aerodynamic diameter:
- > 0 - < 10 other: ). Examination of the data suggests that less than 10% of particles by mass would be likely to be less than 10um in aerodynamic diameter
Particle sizeopen allclose all
- Key result
- Percentile:
- D50
- Mean:
- 25 µm
- Remarks on result:
- other: It was not possible therefore to describe the particle size distribution with a single mass median diameter (MMAD). (migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.)
- Key result
- Percentile:
- other: 0.21
- Mean:
- >= 2.004 µm
- Key result
- Percentile:
- other: 31.85
- Mean:
- >= 202.3 µm
- Key result
- Percentile:
- other: 67.94
- Mean:
- > 2.004 - < 202.3 µm
Particle size distribution at different passages
- No.:
- #1
- Size:
- > 0.723 - < 493.7 µm
Any other information on results incl. tables
The test substance had a particle size distribution between 0.723 and 493.7 um equivalent spherical diameter.
Applicant's summary and conclusion
- Conclusions:
- The particle size distribution of CP-89, 575 was between 0.723 and 493.7JJ.m equivalent spherical diameter, with 0.21% by volume less than 2.004JJ.m, 67.94% between 2.004 and 202.3 JJ.m and 31.85 % greater than 202.3 Jlm.
The proportion of particles with an aerodynamic diameter less than 10 um is likely to be less than 10%, so there would be little potential for inhalation ofCP-89, 575
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