Phosphorodithioic acid, O,O-bis(2-methylpropyl) ester, compd. with N,N-dimethylmethanamine (1:1)

Partition coefficient

Administrative data

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

July 10, 2012 - October 8, 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2012

Report date:

2012

Materials and methods

Test guideline

Test guideline 1

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.8 (Partition Coefficient)

Deviations:

no

Test guideline 2

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)

Deviations:

no

Principles of method if other than guideline:

XRF (X-Ray Fluorescence) method is used to determine the concentration of the test substance by identifying the % of P (phosphorous) present in the investigated solutions.

GLP compliance:

no

Remarks:

the test is well described

Type of method:

flask method

Partition coefficient type:

octanol-water

Test material

Test material information

Constituent 1

Reference substance name:

O,O-bis(2-methylpropyl) sulfanidylphosphonothioate; trimethylazanium

EC Number:

700-910-4

Cas Number:

1354201-99-2

Molecular formula:

C11H28NO2PS2

IUPAC Name:

O,O-bis(2-methylpropyl) sulfanidylphosphonothioate; trimethylazanium

Test material form:

solid

Remarks:

pale yellow glassy solid

Specific details on test material used for the study:

- Name of test material (as cited in study report): S-10713
- Substance type: Straw color, lump solid
- Physical state: solid
- Lot/batch No.: AQ11216TZ
- Expiration date of the lot/batch: July 2013
- Stability: Stable under normal conditions
- Storage condition of test material: Room temperature; in the dark

Study design

Analytical method:

other: XRF (X-Ray Fluorescence) has been applied to determine the concentration of the test substance by identifying the corresponding % of P (phosphorous content)

Results and discussion

Partition coefficient

Type:

log Pow

Partition coefficient:

-0.52

Temp.:

23 °C

Remarks on result:

other: The pH of the investigated solutions has not been determined.

Details on results:

The log Pow of the test substance was determined to be -0.52 ± 0.03, at 23 °C.

Applicant's summary and conclusion

Conclusions:

The log Pow of the test substance was determined to be -0.52 ± 0.03, at 23 °C, in accordance to a method based on both the OECD 107 and EU A.8 guidelines.

Executive summary:

The n-octanol/water partition coefficient of the test material has been determined according to EC A.8 method and OECD test guideline 107.Using the shake flask method, the test material has been determined to have a Log Pow = -0.52 at 23 °C.