Registration Dossier
Registration Dossier
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EC number: 700-718-0 | CAS number: -
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
The EC50 for growth rate reduction (ERC50: 0-72h) for bis[C11-14-(branched and linear)-alkyl]aminium nonadecaoxohexatungstate (EC 700-718-0), based upon results from the surrogate substance, is 0.88 micro g/l. The EC50 for yield inhibition (EYC50: 0-72h) is 0.36 micro g/l. The NOEC is 0.15 micro g/l.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.88 µg/L
- EC10 or NOEC for freshwater algae:
- 0.15 µg/L
Additional information
In an OECD 201 study ("Freshwater Alga and Cyanobacteria, Growth Inhibition Test"), conducted according to GLP, reaction mass of bis(C11-14-alkyl, branched and linear)amine nonadecaoxo hexatungstate (the surrogate substance) has an EC50 for growth rate reduction (ERC50: 0 -72 h) of 0.88 micro g/l and an EC50 for yield inhibition (EYC50: 0-72h) of 0.36 micro g/l (with a 95% confidence interval ranging from 0.17 to 0.76 micro g/l)
The NOEC based on TWA concentrations for both growth rate reduction and yield inhibition is 0.15 micro g/l. The test substance is highly insoluble and the NOEC was derived from a nominal test concentration (Water accommodated fraction (WAF)) of 1.8 mg/l.
Test results were based on two main studies and a worst-case approach was followed to determine the EC and NOEC values, i.e. lowest effect concentrations were used for final toxicity parameters.
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