Registration Dossier
Registration Dossier
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EC number: 230-157-2 | CAS number: 6962-44-3
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1993
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: study performed according to guideline and GLP. No toxicity control. Some deficienies in documentation.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- not specified
- GLP compliance:
- yes
Test material
- Reference substance name:
- N-(2-methoxy-5-methylphenyl)acetamide
- EC Number:
- 230-157-2
- EC Name:
- N-(2-methoxy-5-methylphenyl)acetamide
- Cas Number:
- 6962-44-3
- Molecular formula:
- C10H13NO2
- IUPAC Name:
- N-(2-methoxy-5-methylphenyl)acetamide
- Details on test material:
- - Name of test material (as cited in study report): Acetkresidin 34 TfRS
- Substance type: organic
- Physical state: solid
- Analytical purity: 98.9 %
- Impurities (identity and concentrations):
- Composition of test material, percentage of components:
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- source: waste water treatment plant Frankfurt-Sindlingen. Centrifuged sediment from the activated sludge was washed with water
- Duration of test (contact time):
- 28 d
Initial test substance concentrationopen allclose all
- Initial conc.:
- 174.5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 181.5 mg/L
- Based on:
- test mat.
- Initial conc.:
- 176.5 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
Reference substance
- Reference substance:
- benzoic acid, sodium salt
Results and discussion
% Degradationopen allclose all
- Parameter:
- % degradation (O2 consumption)
- Value:
- 3
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 10
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 11
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 12
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- biodegradation > 60% within 10 days
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- Based on the test results Acetkresidin 34 TTRS is not readily biodegradable.
- Executive summary:
Acetkresidin 34 TTRS was tested for ready biodegradation according to OECD 301F (Manomeric Respirometry Test).After 28 days 12 % degradation could be observed. Therefore, the test item is not readily biodegradable
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