Fatty acids, C6-12, mixed tetraesters with heptanoic acid, pentaerythritol, 3,5,5-trimethylhexanoic acid and valeric acid

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

pyrophoric liquids

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Remarks:

3 substances available for read across

Adequacy of study:

weight of evidence

Justification for type of information:

see the attached justification in section 13 for the full details.

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across source

Key result

Remarks on result:

other: based on the structure, the substance is not expected to ignite in contact with air

Remarks:

Hatcol 3331, Hatcol 3344, Hatol 5236

Interpretation of results:

GHS criteria not met

Conclusions:

The read across for substance, CAS: 156558-98-4; EC: 451-190-0; is based upon the analogous substances to which basic form, degree of substitution of functional groups is not considered to effect the proposed read across for the endpoint of pyrophoric solids. Based on the information available for the read across substances, the substance is not expected to ignite in contact with air.

Reference 2

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Remarks:

3 substances available for readacross

Adequacy of study:

weight of evidence

Justification for type of information:

see the attached justification in section 13 for the full details.

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across source

Key result

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

Remarks:

Hatcol 3331, Hatcol 3344, Hatcol 5236

Interpretation of results:

GHS criteria not met

Conclusions:

The read across for substance, CAS: 156558-98-4; EC: 451-190-0; is based upon the analogous substances to which basic form, degree of substitution of functional groups is not considered to effect the proposed read across for the endpoint of substances in contact with water emit flammable gases. Based on the information available for the read across substances, the substance is not expected to react with water or to emitt flammable gases.

Reference 3

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 September 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

GLP compliance:

yes

Key result

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

Interpretation of results:

GHS criteria not met

Conclusions:

Hatcol 3331 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Executive summary:

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable.

 

The procedure for the determination of the flammability (contact with water) is described in the following guideline:European Economic Community (EEC), EEC directive 92/69 EEC. Part A,Methods for the determination of physico-chemical properties, A-12 "Flammability (contact with water), EEC Publication No. L383, December 1992.

 

Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable.

Hatcol 3331does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Furthermore, no metals. transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air or water.

Moreover, during the addition of a small quantity of the test substance to double distilled water, it was observed that no spontaneous ignition took place and no evolution of gas occurred.

Reference 4

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 September 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

GLP compliance:

yes

Key result

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable.

Hatcol 334 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air orwater.

Moreover, during the addition of a small quantity of the test substance to double distilled water, it was observed that no spontaneous ignition took place and no evolution of gas occurred.

Interpretation of results:

GHS criteria not met

Conclusions:

Hatcol 334 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Executive summary:

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable.

 

The procedure for the determination of the flammability (contact with water) is described in the following guideline: European Economic Community (EEC), EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties, A-12 "Flammability (contact with water)”, EEC Publication No. L383, December 1992.

 

Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable.

Hatcol 334 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air orwater.

Moreover, during the addition of a small quantity of the test substance to double distilled water, it was observed that no spontaneous ignition took place and no evolution of gas occurred.

Reference 5

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

23 September 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.12 (Flammability (Contact with Water))

GLP compliance:

yes

Key result

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable.

Hatcol 5236 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can beconcluded that the test substance is incapable of developing a dangerous amount of(flammable) gas in contact with air, damp air or water.

Moreover, during the addition of a small quantity ofthe test substance to double distilled water, It was observed that no spontaneous ignition took place and no evolution of gas occurred.

Interpretation of results:

GHS criteria not met

Conclusions:

Hatcol 5236 is not flammable.

Executive summary:

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable.

 

The procedure for the determination of the flammability (contact with water) is described in thefollowing guideline:

European Economic Community (EEC), EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties, A-12 "Flammability (contact with water), EEC Publication No. L383, December 1992:

 

Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable.

Hatcol 5236 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities.

Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can beconcluded that the test substance is incapable of developing a dangerous amount of(flammable) gas in contact with air, damp air or water.

Moreover, during the addition of a small quantity ofthe test substance to double distilled water, It was observed that no spontaneous ignition took place and no evolution of gas occurred.

Reference 6

Endpoint:

pyrophoric liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

3 October 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

GLP compliance:

yes

Key result

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition on contact with air (not further specified)

From the structural formula of Hatcol 3331, it can be concluded that Hatcol 3331 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

Interpretation of results:

GHS criteria not met

Conclusions:

From the structural formula of Hatcol 3331, it can be concluded that Hatcol 3331 is not pyrophoric.

Executive summary:

The purpose of the study was to evaluate the pyrophoric properties of the test substance.

The procedure for the determination of the pyrophoric properties is described in the followingguideline:European Economic Community (EEC), EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties, A-13: "Pyrophoric properties of solids and liquids", EEC Publication No. L383, December 1992.

 

From the structural formula of Hatcol 3331, it can be concluded that Hatcol 3331 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

Reference 7

Endpoint:

pyrophoric liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

03 October 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

GLP compliance:

yes

Key result

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition on contact with air (not further specified)

From the structural formula of Hatcol 3344, it can be concluded that Hatcol 3344 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous Ignition a short time after coming Into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

Interpretation of results:

GHS criteria not met

Conclusions:

From the structural formula of Hatcol 3344, it can be concluded that Hatcol 3344 is not pyrophoric.

Executive summary:

The purpose of the study was to evaluate the pyrophoric properties of the test substance.

The procedure for the determination of the pyrophoric properties Is described In the following guideline: European Economic Community (EEC), EEC directive 92169 EEC, Part A, Methods for thedetermination ofphysico-chemical properties, A-13: "Pyrophoric properties of solids and liquids", EEC Publication No. L383, December 1992.

 

From the structural formula of Hatcol 3344, it can be concluded that Hatcol 3344 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous Ignition a short time after coming Into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

Reference 8

Endpoint:

pyrophoric liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

3 October 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Study performed in accordance with EU test guidelines in compliance with GLP.

Qualifier:

according to guideline

Guideline:

EU Method A.13 (Pyrophoric Properties of Solids and Liquids)

GLP compliance:

yes

Key result

Test procedure:

ignition time on contact with air

Remarks on result:

no ignition on contact with air (not further specified)

From the structural formula of Hatcol 5236, it can be concluded that Hatcol 5236 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition in a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling show that the test substance does not ignite coming in contact with air.

Interpretation of results:

non flammable

Remarks:

Migrated information

Conclusions:

From the structural formula of Hatcol 5236, it can be concluded that Hatcol 5236 is not pyrophoric.

Executive summary:

The purpose of the study was to evaluate the pyrophonc properties of the test substance.

 

The procedure for the determination of the pyrophoric properties is described in the following guideline:European Economic Community (EEC), EEC directive 92/69 EEC, Part A, Methods for the determination of physico-chemical properties, A-13: "Pyrophoric properties of solids and liquids", EEC Publication No. L383, December 1992.

 

From the structuralformula of Hatcol 5236, it can be concluded that Hatcol 5236 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling show that the test substance does not ignite coming in contact with air.

Description of key information

The read across for substance, CAS: 156558-98-4; EC: 451-190-0; is based upon the analogous substances to which basic form, degree of substitution of functional groups is not considered to effect the proposed read across for the endpoint of pyhorphic solids. Based on the information available for the read across substances, the substance is not expected to ignite in contact with air or react with water to emit flammable gases.

Key value for chemical safety assessment

Flammability:

non flammable

Additional information

HATCOL 5236

Flammability (contact with water):

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable. Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable. Hatcol 5236 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities. Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air or water. Moreover, during the addition of a small quantity of the test substance to double distilled water, It was observed that no spontaneous ignition took place and no evolution of gas occurred.

Flammability (pyrophoric properties):

The purpose of the study was to evaluate the pyrophonc properties of the test substance. From the structural formula of Hatcol 5236, it can be concluded that Hatcol 5236 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling show that the test substance does not ignite coming in contact with air.

HATCOL 3344

Flammability (contact with water):

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable. Substances which, in contact with water or damp air, evolve highly flammable gases in dangerous quantities at a minimum rate of 1 litre/kg per hour are highly flammable. Hatcol 334 does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities. Furthermore, no metals, transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air or water. Moreover, during the addition of a small quantity of the test substance to double distilled water, it was observed that no spontaneous ignition took place and no evolution of gas occurred.

Flammability (pyrophoric properties):

The purpose of the study was to evaluate the pyrophoric properties of the test substance.  From the structural formula of Hatcol 3344, it can be concluded that Hatcol 3344 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous Ignition a short time after coming Into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

HATCOL 3331:

Flammability (contact with water):

The purpose of the study was to evaluate whether the reaction of the test substance with water or damp air leads to the development of dangerous amounts of gas or gases which may be highly flammable. Hatcol 3331does not contain groups that might lead to evolution of highly flammable gases in dangerous quantities. Furthermore, no metals. transition metals, boron or silicon are present. Therefore, it can be concluded that the test substance is incapable of developing a dangerous amount of (flammable) gas in contact with air, damp air or water. Moreover, during the addition of a small quantity of the test substance to double distilled water, it was observed that no spontaneous ignition took place and no evolution of gas occurred.

Flammability (pyrophoric properties):

The purpose of the study was to evaluate the pyrophoric properties of the test substance. From the structural formula of Hatcol 3331, it can be concluded that Hatcol 3331 is not pyrophoric. The test substance does not contain any chemical group that might lead to spontaneous ignition a short time after coming into contact with air at room temperature (circa 20°C). Furthermore, experience in handling shows that the test substance does not ignite coming in contact with air.

Justification for classification or non-classification

Based on the available information the structural analogue substances used for read across purposes do not trigger any requirements for classification. Therefore the substance to be registered is Not Classified as a Flammable material.