Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-425-1 | CAS number: 106-70-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (72 h) = 61 mg/L (nominal) for Pseudokirchneriella subcapitata (OECD 201)
EC50 (72 h) = 11 mg/L (mean measured concentration) for Pseudokirchneriella subcapitata (OECD 201)
NOEC (72 h) = 12.5 mg/L (nominal) for Pseudokirchneriella subcapitata (OECD 201)
NOEC (72 h) = 2.7 mg/L (mean measured concentration) for Pseudokirchneriella subcapitata (OECD 201)
EC50 (96 h) = 16.2 mg/L (QSAR)
Key value for chemical safety assessment
Additional information
One study evaluating the toxicity of methyl hexanoate (CAS No. 106-70-7) to algae is available (Kimmel, 2013). This test was conducted according to OECD Guideline 201, under GLP conditions. Pseudokirchneriella subcapitata was exposed to the test substance for 72 hours within static water regime at 22 °C. Measurements of test concentrations (6.25, 12.5, 25, 50 and 100 mg/L, nominal) were performed through GC analysis. After 72 hours, significant effects on algal growth rate were reported at nominal concentrations of 25, 50 and 100 mg/L. The EC50 (72 h, growth rate) was determined to be 61 mg/L (nominal concentration) and the NOEC (72 h, growth rate) = 12.5 mg/L (nominal concentration), corresponding to measured values of 11 mg/L and 2.7 mg/L, respectively. Additionally, a QSAR calculation (ECOSAR v1.00) was performed, resulting in an EC50 (96 h) of 16.2 mg/L (green algae, calculation for neutral organics).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
